[email protected]. Phone: 319-335-0194. Office: Primary Office: 106C Medical Research Center 25 S. Grand Avenue. Website: ... Secondary Faculty (Iowa) WebMay 7, 2024 · Background Skeletal muscle gradually loses mass, strength, endurance, and oxidative capacity during aging. Studies of bioenergetics and protein turnover show that mitochondria mediate this decline in function. Mitochondria cristae are essential for the production of ATP. While mitochondrial aging is associated with endoplasmic reticulum …
Mitochondrial Dysfunction in Heart Failure and Arrhythmia
WebJan 5, 2024 · Mice with deletion of complex I subunit Ndufs4 develop mitochondrial encephalomyopathy resembling Leigh syndrome (LS). We report that LS mice also develop severe cardiac bradyarrhythmia and diastolic dysfunction. Human induced pluripotent stem cell-derived cardiomyocytes (iPS-CMs) with Ndufs4 deletion recapitulate LS … WebYi Chu 1 , Renny S Lan 2 , Rui Huang 3 , Hao Feng 1 , Rahul Kumar 4 , Sanjana Dayal 4 , Kung-Sik Chan 3 , Dao-Fu Dai 1 Affiliations 1 Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, Iowa. shannon wilber menominee county
Metabolic rescue ameliorates mitochondrial encephalo
WebSep 27, 2024 · The University of Iowa. Iowa City, United States. Dao-Fu Dai. Overview; Bio; Network 1; Publications 85; Editorial Contributions 1; ... Dao-Fu Dai; Sheng-Nan Wu; International Journal of Molecular Sciences. Published on 22 Feb 2024. 0 views XX downloads; XX citations; Cardiac Specific Overexpression of Transcription Factor EB … WebMar 4, 2024 · Dai DF 1. Author information ... Daneshgar N, 0000-0002-0703-0494, The University of Iowa Roy J and Lucille A Carver College of Medicine; Frontiers in Pediatrics, 04 Mar 2024, 10 ... Nastaran Daneshgar, 1 Peir-In Liang, 1 , 2 Christina J. Michels, 3 Carla M. Nester, 3 , 4 Lyndsay A. Harshman, 3 , * , † and Dao-Fu Dai 1 , * , † Author ... WebMay 25, 2024 · Using electronic health records and biobank samples, we found that the transcription factor SOX6 is associated with abdominal and thoracic aortic aneurysm and its expression is upregulated in tissue from patients affected by those diseases. Laboratory-wide association study (LabWAS) provides several clinical laboratory measurements … pom pom and megaphone