C-terminal binding protein 2

WebOct 25, 2024 · BACKGROUND Recent studies have illustrated that the transcription co-repressor, C-terminal binding protein 1 (CtBP1), links the metabolic alterations to transcription controls in proliferation, EMT, genome stability, metabolism, and lifespan, but whether CtBP1 affects the cellular redox homeostasis is unexplored. This study was … WebSep 23, 2024 · The 35 kDa OCP is structurally and functionally modular, consisting of an N-terminal effector domain (NTD) and a C-terminal regulatory domain (CTD); a carotenoid spans the two domains.

A gene truncation strategy generating N- and C-terminal …

WebGuanylate-Binding Protein. The guanylate binding proteins (GBPs) are interferon-induced GTPases of the dynamin superfamily (reviewed in Ref. 75). ... Several members, such as murine and human GBP1, − 2 and − 5 also contain a C-terminal CaaX box required for isoprenylation (farnesylation, geranyl/geranylation) and membrane anchoring ... WebNov 2, 2024 · Here we describe a hepatic system in this context orchestrated by the transcriptional corepressor C-terminal binding protein 2 (CtBP2) that harbors metabolite-sensing capabilities. The repressor ... iptg synthesis https://ibercusbiotekltd.com

CTBP1 - Wikipedia

WebApr 12, 2024 · Background: Tocotrienol, a type of vitamin E, is well known for its anti-cancer and other biological activities. This systematic review aims to summarize the involvement of endoplasmic reticulum stress (ERS) and subsequent unfolded protein response (UPR) as the underlying molecular mechanisms for the anticancer properties of tocotrienol. … WebAug 1, 2015 · 1. Introduction. The CtBP (C-terminal binding protein) interacting protein (CtIP) was initially identified as part of the CtBP transcriptional corepressor complex that mediates repression of many genes and plays important roles in development and cancer [1], [2].In addition, CtIP was found to bind directly to the retinoblastoma (Rb) protein [3], … WebPTHR46029:SF2 C-TERMINAL-BINDING PROTEIN 1 1 hit; PROSITE. View protein in PROSITE; PS00065 D_2_HYDROXYACID_DH_1 1 hit; PS00671 D_2_HYDROXYACID_DH_3 1 hit; Pfam. View protein in Pfam; PF00389 2-Hacid_dh 1 hit; PF02826 2-Hacid_dh_C 1 hit; SUPFAM. SSF52283 Formate/glycerate dehydrogenase … iptg06ase14-5sn0f7

ACYL-CoA-BINDING DOMAIN-CONTAINING PROTEIN 4; …

Category:Structural characterization of the C-terminal domain of SARS-CoV …

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C-terminal binding protein 2

ACYL-CoA-BINDING DOMAIN-CONTAINING PROTEIN 4; ACBD4

WebMay 22, 2024 · The basic residues (511 HRR 513) and C-terminal R 525 (X) 2-5 PY motif are necessary and sufficient for nuclear import, while also being required for receptor binding and protein function, respectively . Wang et al. discovered the PY-NLS sequence 66 TLLLRETMNNLGVSDHAVLSRKTPQPY 92 at the N terminus of the human … WebPTHR46029:SF3 C-TERMINAL-BINDING PROTEIN 2 1 hit; PROSITE. View protein in PROSITE; PS00671 D_2_HYDROXYACID_DH_3 1 hit; Pfam. View protein in Pfam; PF00389 2-Hacid_dh 1 hit; PF02826 2-Hacid_dh_C 1 hit; SUPFAM. SSF52283 Formate/glycerate dehydrogenase catalytic domain-like 1 hit;

C-terminal binding protein 2

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WebCalponin 1 is a basic smooth muscle protein that in humans is encoded by the CNN1 gene.. The CNN1 gene is located at 19p13.2-p13.1 in the human chromosomal genome and contains 7 exons, encoding the protein calponin 1, an actin filament-associated regulatory protein. Human calponin 1 is a 33.2-KDa protein consists of 297 amino acids with an … WebNov 19, 2012 · C-TERMINAL-BINDING PROTEIN 2; CTBP2 HGNC Approved Gene Symbol: CTBP2 Cytogenetic location: 10q26.13 Genomic coordinates (GRCh38): …

WebApr 24, 2024 · C-terminal binding protein 2 (CtBP2) is elevated in epithelial ovarian cancer, especially in the aggressive and highly lethal subtype, high-grade serous ovarian cancer (HGSOC). However, whether ... Web2 days ago · The C-terminal function of the KsgA protein was investigated in vitro and in vivo. Results: The 3D conformations of KsgA, MutM, and Nei were compared at UCSF …

WebCorepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. WebRecently, it was reported that mutations in the ubiquitin-like protein ubiquilin-2 (UBQLN2) are associated with X-linked amyotrophic lateral sclerosis (ALS), and that both wild-type …

WebIsoform-2 contains 305 amino acids and has an N-terminal acyl-CoA-binding domain (ACBD), followed by a FFAT-like motif, a coiled-coil domain, and a C-terminal …

ipth blutwertWebSep 3, 2012 · The C-terminal binding protein-2 (CtBP2) was identified as a tumor antigen in epithelial ovarian cancer using a reverse capture antibody array. 2 We sought to … ipth blutWebOct 29, 2009 · Sequence analysis predicted that the 1,325-amino acid protein, like other ABC transporters, contains nucleotide-binding folds and 12 transmembrane-spanning helices in 2 hydrophobic domains. Northern blot analysis revealed ubiquitous expression of an approximately 6.0-kb transcript that is highest in prostate and lowest in liver and … ipth e-learningWebC-Terminal of E1A Binding Protein 1 Enhances the Migration of Gastric Epithelial Cells and Has a Clinicopathologic Significance in Human Gastric Carcinoma [Retraction] … orchard v lee case summaryWebJan 8, 2024 · CtBP2 interacts with TGIF to promote the progression of esophageal squamous cell cancer through the Wnt/betacatenin pathway. The transcriptional … orchard v lee caseWebC-Terminal of E1A Binding Protein 1 Enhances the Migration of Gastric Epithelial Cells and Has a Clinicopathologic Significance in Human Gastric Carcinoma [Retraction] Wang C, Wang M, Xing B, et al. Onco Targets Ther . 2024;12:5189–5200. The Editor and Publisher of OncoTargets and Therapy wish to retract the published article. ipth 85WebThe CtBP1 protein was originally identified as a human protein that bound a PLDLS motif in the C-terminus of adenovirus E1A proteins. It and the related protein CTBP2 were later … orchard vale naturals